US experiment flown on the Soviet biosatellite Cosmos 1667

Two male young-adult rhesus monkeys were flown on the Soviet Biosatellite Cosmos 1667 for seven days from July 10-17, 1985. Both animals were instrumented to record neurophysiological parameters. One animal, Gordyy, was additionally instrumented to record cardiovascular changes. Space capsule and environmental parameters were very similar to those of previous missions. On Cosmos 1514, which flew for five days in 1983, one animal was fitted with a left carotid artery cuff to measure blood pressure and flow velocity. An additional feature of Cosmos 1667 was a postflight control study using the flight animal. Intermittent postural tilt tests were also conducted before and after spaceflight and synchronous control studies, to simulate the fluid shifts associated with spaceflight. The experiment results support the conclusion derived from Cosmos 1514 that significant cardiovascular changes occur with spaceflight. The changes most clearly seen were rapid initial decreases in heart rate and further decreases with continued exposure to microgravity. The triggering mechanism appeared to be a headward shift in blood and tissue fluid volume which, in turn, triggered adaptive cardiovascular changes. Adaptive changes took place rapidly and began to stabilize after the first two days of flight. However, these changes did not plateau in the animal by the last day of the mission

A Magnetotelluric Investigation of the Cascadia Subduction Zone Plate Interface

49 pages. A thesis presented to the Department of Physics and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2017Zones of reduced ‘Episodic Tremor and Slip’ along the Cascadia Subduction Zone (CSZ) are known to correspond to fluids anomalies at the Juan de Fuca-North American plate interface. We process Magnetotelluric models of the conductivity of the CSZ to isolate conductivity values adjacent to plate interface, as well as to compute a vertical conductivity ‘gradient’ away from the interface. We compare the average conductivity and non-volcanic tremor density in windows of various sizes along the Mantle Wedge Corner (MWC) and compute their correlation. Tremor and conductivity correlate moderately along a window extending 100km up-dip from the MWC. The correlation is weaker for windows of different sizes or those centered down-dip, which suggests a coupling mechanism along the interface up-dip of the MWC, linking conductivity and tremor occurrence. The conductivity gradient is anomalously low surrounding regions where serpentinization reactions are known to take place. Finally, we investigate the regions near crustal faults, around which tremor occurrence is suppressed. We find that conductivity anomalies do not consistently occur around these faults, and thus that the effect of these faults on tremor is likely mechanical

Scientific access into Mercer Subglacial Lake: Scientific objectives, drilling operations and initial observations

The Subglacial Antarctic Lakes Scientific Access (SALSA) Project accessed Mercer Subglacial Lake using environmentally clean hot-water drilling to examine interactions among ice, water, sediment, rock, microbes and carbon reservoirs within the lake water column and underlying sediments. A ∼0.4 m diameter borehole was melted through 1087 m of ice and maintained over ∼10 days, allowing observation of ice properties and collection of water and sediment with various tools. Over this period, SALSA collected: 60 L of lake water and 10 L of deep borehole water; microbes \u3e0.2 μm in diameter from in situ filtration of ∼100 L of lake water; 10 multicores 0.32-0.49 m long; 1.0 and 1.76 m long gravity cores; three conductivity-temperature-depth profiles of borehole and lake water; five discrete depth current meter measurements in the lake and images of ice, the lake water-ice interface and lake sediments. Temperature and conductivity data showed the hydrodynamic character of water mixing between the borehole and lake after entry. Models simulating melting of the ∼6 m thick basal accreted ice layer imply that debris fall-out through the ∼15 m water column to the lake sediments from borehole melting had little effect on the stratigraphy of surficial sediment cores

Environmentally clean access to Antarctic subglacial aquatic environments

Subglacial Antarctic aquatic environments are important targets for scientific exploration due to the unique ecosystems they support and their sediments containing palaeoenvironmental records. Directly accessing these environments while preventing forward contamination and demonstrating that it has not been introduced is logistically challenging. The Whillans Ice Stream Subglacial Access Research Drilling (WISSARD) project designed, tested and implemented a microbiologically and chemically clean method of hot-water drilling that was subsequently used to access subglacial aquatic environments. We report microbiological and biogeochemical data collected from the drilling system and underlying water columns during sub-ice explorations beneath the McMurdo and Ross ice shelves and Whillans Ice Stream. Our method reduced microbial concentrations in the drill water to values three orders of magnitude lower than those observed in Whillans Subglacial Lake. Furthermore, the water chemistry and composition of microorganisms in the drill water were distinct from those in the subglacial water cavities. The submicron filtration and ultraviolet irradiation of the water provided drilling conditions that satisfied environmental recommendations made for such activities by national and international committees. Our approach to minimizing forward chemical and microbiological contamination serves as a prototype for future efforts to access subglacial aquatic environments beneath glaciers and ice sheets

The asymmetric aza-silyl-prins reaction: Synthesis of enantiopure piperidines

The design and development of the first asymmetric aza-silyl-Prins reaction is reported, giving rise to valuable and diverse piperidines and pipecolic acid derivatives in both high yields and as single enantiomers. The creation of a novel chiral auxiliary-homoallylic amine for the aza-silyl-Prins reaction is essential to its success